umbralisib (TGR-1202)

10mM in DMSO

Reagent Code: #239233
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CAS Number 1532533-67-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 571.55 g/mol
Formula C₃₁H₂₄F₃N₅O₃
badge Registry Numbers
MDL Number MFCD28386165
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in the treatment of certain B-cell malignancies, particularly relapsed or refractory mantle cell lymphoma and chronic lymphocytic leukemia. It functions as a dual inhibitor of PI3K-delta and casein kinase-1-epsilon, helping to block signaling pathways that promote tumor growth and survival. Its selectivity may reduce immune-related toxicities compared to other inhibitors, making it a valuable option in patients who have failed prior therapies. Currently under investigation in clinical trials to expand its use in combination regimens and other hematologic cancers.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿9,600.00

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