Torin-1

2mM in DMSO

Reagent Code: #239225
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CAS Number 1222998-36-8

science Other reagents with same CAS 1222998-36-8

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Weight 607.62 g/mol
Formula C₃₅H₂₈F₃N₅O₂
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Torin-1 is a potent and selective inhibitor of mTOR (mechanistic target of rapamycin), a key protein kinase involved in regulating cell growth, proliferation, and survival. It is widely used in research to study the mTOR signaling pathway, particularly the mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). Due to its high specificity and ability to fully inhibit mTOR activity, Torin-1 is employed in cellular and molecular biology experiments to induce autophagy, suppress protein synthesis, and investigate metabolic regulation. It has also been utilized in cancer research to examine the effects of mTOR inhibition on tumor cell growth and survival, showing potential in sensitizing certain cancer cells to other therapies. Additionally, Torin-1 is used in aging and neurodegenerative disease studies, where modulation of mTOR signaling is linked to lifespan extension and protection against protein aggregation. Its application remains primarily in preclinical research, serving as a tool compound for understanding disease mechanisms and evaluating therapeutic strategies.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿5,500.00

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Torin-1
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Torin-1 is a potent and selective inhibitor of mTOR (mechanistic target of rapamycin), a key protein kinase involved in regulating cell growth, proliferation, and survival. It is widely used in research to study the mTOR signaling pathway, particularly the mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). Due to its high specificity and ability to fully inhibit mTOR activity, Torin-1 is employed in cellular and molecular biology experiments to induce autophagy, suppress protein synthesis, and investigate metabolic regulation. It has also been utilized in cancer research to examine the effects of mTOR inhibition on tumor cell growth and survival, showing potential in sensitizing certain cancer cells to other therapies. Additionally, Torin-1 is used in aging and neurodegenerative disease studies, where modulation of mTOR signaling is linked to lifespan extension and protection against protein aggregation. Its application remains primarily in preclinical research, serving as a tool compound for understanding disease mechanisms and evaluating therapeutic strategies.
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