Torin 2
10mM in DMSO
Reagent
Code: #239214
CAS Number
1223001-51-1
blur_circular Chemical Specifications
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Molecular Information
Weight
432.40 g/mol
Formula
C₂₄H₁₅F₃N₄O
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Storage & Handling
Storage
-20°C
description Product Description
Torin 2 is primarily used in biomedical research as a potent and selective inhibitor of mTOR (mechanistic target of rapamycin), a key protein kinase involved in cell growth, proliferation, and survival. It effectively suppresses both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2), making it a valuable tool for studying signaling pathways related to cancer, metabolism, and aging. Due to its high selectivity and improved pharmacokinetic properties over earlier inhibitors, Torin 2 is widely used in preclinical studies to investigate tumor suppression, autophagy induction, and cellular response to stress. It also serves as a reference compound in drug development targeting mTOR-driven diseases, including various cancers and metabolic disorders.
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