Tert-Butyl 6-(bromomethyl)-1H-indazole-1-carboxylate
≥95%
Reagent
Code: #238183
CAS Number
1126424-54-1
blur_circular Chemical Specifications
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Molecular Information
Weight
311.17 g/mol
Formula
C₁₃H₁₅BrN₂O₂
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Registry Numbers
MDL Number
MFCD21364527
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its bromomethyl group allows for easy functionalization, enabling coupling reactions with nucleophiles such as amines or thiols to form more complex molecules. Commonly employed in medicinal chemistry for building blocks in drug discovery programs targeting inflammatory diseases and oncology. Also utilized in the preparation of proteolysis-targeting chimeras (PROTACs) due to its ability to link targeting ligands with E3 ligase binders.
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