S961 is primarily used as a selective inhibitor of the insulin receptor (IR) in biochemical and pharmacological research. It enables scientists to study insulin signaling pathways by specifically blocking IR activity without significantly affecting the insulin-like growth factor-1 receptor (IGF-1R), making it a valuable tool in diabetes and cancer research. Due to its high potency and selectivity, S961 is often applied in vivo and in vitro to modulate glucose metabolism and investigate metabolic disorders. It is also utilized in studies exploring the role of insulin signaling in cell growth, proliferation, and survival, particularly in tumor models where insulin receptor overexpression is observed.