Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting BTK (Bruton's tyrosine kinase) for the treatment of autoimmune diseases and certain cancers. Its spirocyclic structure and stereochemistry enhance selectivity and binding affinity to the target enzyme. The compound's fluorinated fluorenyl group improves metabolic stability and membrane permeability, making it valuable in optimizing drug candidates. It is also employed in structure-activity relationship (SAR) studies to develop more effective and selective therapeutic agents.