4-(((6S,9S,9aS)-1-(Benzylcarbamoyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)octahydro-2H-pyrazino[2,1-c][1,2,4]triazin-6-yl)methyl)phenyl dihydrogen phosphate

≥99%

Reagent Code: #233558
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CAS Number 1422253-38-0

science Other reagents with same CAS 1422253-38-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 658.64 g/mol
Formula C₃₃H₃₅N₆O₇P
badge Registry Numbers
MDL Number MFCD12196918
inventory_2 Storage & Handling
Density 1.48±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K), specifically targeting the p110δ subunit, which plays a crucial role in immune cell signaling pathways involved in inflammation and oncogenesis. Developed for the treatment of autoimmune disorders and certain cancers, particularly hematological malignancies such as leukemia and lymphoma.

Due to its ability to inhibit B and T cell activation associated with inflammation and immune dysregulation, this compound demonstrates potential in managing chronic immune-mediated diseases, including rheumatoid arthritis and systemic lupus erythematosus (SLE).

In preclinical and research studies, it shows activity in suppressing tumor cell proliferation at the molecular level and synergizes with other chemotherapeutics to enhance efficacy, positioning it as a valuable option for combination therapies in treatment-resistant patients.

Its molecular structure confers high binding affinity and enhanced metabolic stability, making it a promising candidate for oral drug formulations. Currently in clinical development stages, with ongoing assessments of bioavailability, long-term toxicity, safety profiles, and side effects for advanced therapeutic applications.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿10,090.00
inventory 50mg
10-20 days ฿19,480.00

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4-(((6S,9S,9aS)-1-(Benzylcarbamoyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)octahydro-2H-pyrazino[2,1-c][1,2,4]triazin-6-yl)methyl)phenyl dihydrogen phosphate
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Used in pharmaceutical research as a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K), specifically targeting the p110δ subunit, which plays a crucial role in immune cell signaling pathways involved in inflammation and oncogenesis. Developed for the treatment of autoimmune disorders and certain cancers, particularly hematological malignancies such as leukemia and lymphoma.

Due to its ability to inhibit B and T cell activation associated with inflammation and immune dysregulation,

Used in pharmaceutical research as a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K), specifically targeting the p110δ subunit, which plays a crucial role in immune cell signaling pathways involved in inflammation and oncogenesis. Developed for the treatment of autoimmune disorders and certain cancers, particularly hematological malignancies such as leukemia and lymphoma.

Due to its ability to inhibit B and T cell activation associated with inflammation and immune dysregulation, this compound demonstrates potential in managing chronic immune-mediated diseases, including rheumatoid arthritis and systemic lupus erythematosus (SLE).

In preclinical and research studies, it shows activity in suppressing tumor cell proliferation at the molecular level and synergizes with other chemotherapeutics to enhance efficacy, positioning it as a valuable option for combination therapies in treatment-resistant patients.

Its molecular structure confers high binding affinity and enhanced metabolic stability, making it a promising candidate for oral drug formulations. Currently in clinical development stages, with ongoing assessments of bioavailability, long-term toxicity, safety profiles, and side effects for advanced therapeutic applications.

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