(2S,4R)-1-((S)-2-(4-(4-(5-((Furan-2-ylmethyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)benzamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

98%

Reagent Code: #233412
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CAS Number 2688842-08-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 832.97 g/mol
Formula C₄₃H₄₈N₁₀O₆S
badge Registry Numbers
MDL Number MFCD32701932
inventory_2 Storage & Handling
Density 1.40±0.1 g/cm3(Predicted)
Storage 2-8°C, away from light, dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), this compound is being investigated for the treatment of autoimmune diseases and certain B-cell malignancies. It modulates B-cell receptor signaling, leading to reduced activation, proliferation, and survival of malignant or autoreactive B cells. Due to its high selectivity and irreversible binding to BTK, it shows promise in conditions such as rheumatoid arthritis, chronic lymphocytic leukemia (CLL), and mantle cell lymphoma (MCL). Its structure enables improved pharmacokinetic properties, including oral bioavailability and sustained target inhibition, making it suitable for once-daily dosing in clinical settings.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿11,200.00
inventory 50mg
10-20 days ฿17,900.00

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