(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
98%
Reagent
Code: #233175
CAS Number
2223677-64-1
science Other reagents with same CAS 2223677-64-1
blur_circular Chemical Specifications
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Molecular Information
Weight
422.87 g/mol
Formula
C₂₂H₂₀ClFN₄O₃
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Storage & Handling
Storage
2-8°C, avoiding light
description Product Description
Used as an intermediate in the synthesis of targeted cancer therapies, particularly in the development of tyrosine kinase inhibitors. It plays a role in blocking signaling pathways that promote tumor growth, especially in non-small cell lung cancer and other solid tumors. Its structure allows selective inhibition of epidermal growth factor receptor (EGFR) mutants, including those resistant to earlier generations of inhibitors. This compound contributes to improved potency and selectivity in next-generation oncology drugs.
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