1-((S)-4-(7-((R)-6-Amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

98%

Reagent Code: #232528
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CAS Number 2417987-45-0

science Other reagents with same CAS 2417987-45-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 622.06 g/mol
Formula C₂₉H₃₂ClF₄N₇O₂
thermostat Physical Properties
Boiling Point 743.4±70.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.344±0.06 g/cm3(Predicted)
Storage -20°C, light-proof, inert gas

description Product Description

Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to specific tyrosine kinases involved in tumor growth and proliferation. It is employed in the development of pharmaceuticals for treating non-small cell lung cancer and other solid tumors. The compound's design supports improved metabolic stability and bioavailability in drug formulations. It is also utilized in structure-activity relationship (SAR) studies to optimize inhibitor potency and selectivity.

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Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿7,870.00
inventory 50mg
10-20 days ฿26,550.00

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1-((S)-4-(7-((R)-6-Amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
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Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to specific tyrosine kinases involved in tumor growth and proliferation. It is employed in the development of pharmaceuticals for treating non-small cell lung cancer and other solid tumors. The compound's design supports improved metabolic stability and bioavailability in drug formulations. It is also utilized in structure-activity relationship (SAR)

Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to specific tyrosine kinases involved in tumor growth and proliferation. It is employed in the development of pharmaceuticals for treating non-small cell lung cancer and other solid tumors. The compound's design supports improved metabolic stability and bioavailability in drug formulations. It is also utilized in structure-activity relationship (SAR) studies to optimize inhibitor potency and selectivity.

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