(R)-2-(3-(4-Amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-methyl-4-(4-(oxetan-3-yl)piperazin-1-yl)pent-2-enenitrile

≥98%

Reagent Code: #232260
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CAS Number 1575591-66-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 665.76 g/mol
Formula C₃₆H₄₀FN₉O₃
inventory_2 Storage & Handling
Storage -20°C, sealed, dry, light-proof

description Product Description

Used as a potent inhibitor in targeted cancer therapies, particularly in the treatment of certain leukemias and solid tumors. It functions by selectively blocking signaling pathways involved in tumor cell proliferation and survival, especially those driven by dysregulated kinase activity. Due to its structural specificity, it demonstrates high binding affinity to mutant forms of kinases that are resistant to conventional inhibitors, making it valuable in overcoming drug resistance. Its design allows for improved pharmacokinetic properties, including oral bioavailability and blood-brain barrier penetration, enabling efficacy in central nervous system malignancies. Commonly employed in clinical research and development for advanced-stage cancers with limited treatment options.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿10,790.00
inventory 50mg
10-20 days ฿18,340.00
inventory 100mg
10-20 days ฿34,710.00
inventory 250mg
10-20 days ฿76,920.00

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