(R)-tert-Butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate
97%(HPLC)
science Other reagents with same CAS 668273-75-4
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description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly targeting cancer pathways. Its structure supports binding to specific enzyme sites involved in tumor growth, exhibits good cell membrane permeability, and shows high specificity to biological targets such as kinases associated with abnormal cell proliferation, making it valuable in developing targeted therapies.
Generally, compounds of this type are developed as potent and selective inhibitors for treating various cancers, especially those involving mutations in proteins that regulate cell growth. Its modifiable structure makes it an important molecule in drug discovery to improve efficacy and reduce side effects.
Additionally, the carbamate group in its structure enhances stability and controls the release of the active substance in the body, making it suitable for development as oral drug candidates. Commonly applied in medicinal chemistry for optimizing drug candidates due to its favorable solubility and stability properties. Also utilized in structure-activity relationship (SAR) studies to enhance potency and selectivity of anticancer agents.
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