(R)-7-(But-2-Ynyl)-8-(3-(1,3-Dioxoisoindolin-2-Yl)Piperidin-1-Yl)-3-Methyl-1-((4-Methylquinazolin-2-Yl)Methyl)-1H-Purine-2,6(3H,7H)-Dione
97%
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description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), this compound plays a key role in the development of treatments for autoimmune diseases and certain B-cell malignancies. Its structure allows for high binding affinity to the BTK enzyme, effectively modulating signaling pathways involved in cell proliferation and survival. Due to its (R)-enantiomeric configuration, it exhibits improved pharmacokinetic properties and reduced off-target effects compared to racemic counterparts. It is primarily investigated in preclinical studies for conditions such as chronic lymphocytic leukemia, rheumatoid arthritis, and other disorders driven by aberrant B-cell activation.
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