Resatorvid is primarily used in research settings to inhibit the p38 mitogen-activated protein kinase (p38 MAPK) pathway, which plays a key role in inflammation and cellular stress responses. It helps scientists study inflammatory processes and has been investigated for its potential in reducing the production of pro-inflammatory cytokines such as TNF-α. Due to its inhibitory effect, resatorvid is applied in models of neurodegenerative diseases, septic shock, and autoimmune disorders to evaluate the therapeutic impact of blocking p38 signaling. It is not used clinically but serves as a valuable tool compound in pharmacological and biochemical research.