R788 (Fostamatinib) Disodium

2mM in DMSO

Reagent Code: #229745
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CAS Number 1025687-58-4

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scatter_plot Molecular Information
Weight 624.42 g/mol
Formula C₂₃H₂₄FN₆O₉P·₂Na
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MDL Number MFCD15146370
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in the treatment of autoimmune diseases, particularly chronic immune thrombocytopenia (ITP), where it helps increase platelet counts by inhibiting spleen tyrosine kinase (Syk). This action reduces the immune system's destruction of platelets, making it beneficial for patients who have not responded well to other therapies like corticosteroids or splenectomy. Investigated for use in other immune-mediated conditions such as rheumatoid arthritis and autoimmune hemolytic anemia due to its role in modulating immune cell signaling. Also explored in inflammatory diseases because of its impact on Fc receptor-mediated inflammation pathways.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿3,590.00

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