Used in the treatment of metastatic colorectal cancer and advanced gastrointestinal stromal tumors, particularly in patients who have already undergone prior therapy. It functions as a multi-kinase inhibitor, blocking several enzymes involved in tumor angiogenesis, oncogenesis, and the tumor microenvironment. Also approved for use in hepatocellular carcinoma after progression on sorafenib. Helps slow tumor growth and extend survival in advanced cancer cases.