Roblitinib (FGF401)
2mM in DMSO
Reagent
Code: #229584
CAS Number
1708971-55-4
science Other reagents with same CAS 1708971-55-4
blur_circular Chemical Specifications
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Molecular Information
Weight
506.56 g/mol
Formula
C₂₅H₃₀N₈O₄
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Registry Numbers
MDL Number
MFCD31381923
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Storage & Handling
Storage
-20°C
description Product Description
Used in targeted cancer therapy, particularly for tumors driven by FGF19 signaling, such as hepatocellular carcinoma. Acts as a selective inhibitor of fibroblast growth factor receptor 4 (FGFR4), blocking downstream pathways involved in cell proliferation and survival. Currently under investigation in clinical trials to evaluate efficacy and safety in advanced solid tumors. Shows potential for treating patients with FGF19-positive cancers who have limited response to conventional therapies.
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