3-Quinolinecarbonitrile, 6-amino-4-[(3-chloro-4-fluorophenyl)amino]-8-fluoro-
95%
Reagent
Code: #228508
CAS Number
915369-88-9
blur_circular Chemical Specifications
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Molecular Information
Weight
330.7 g/mol
Formula
C₁₆H₉ClF₂N₄
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Storage & Handling
Storage
2-8°C, dry, closed
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly EGFR inhibitors like Afatinib, in targeted cancer therapies. Its structure enables binding to specific enzyme sites, making it valuable in developing drugs that inhibit abnormal cell growth. Commonly applied in pharmaceutical research for treating solid tumors, such as non-small cell lung cancer. Also utilized in the preparation of small molecule inhibitors that block signaling pathways in cancer cells. Shows high potency in compounds designed to overcome drug resistance in tumor cells.
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