3-Quinolinecarbonitrile, 6-amino-4-[(3-chloro-4-fluorophenyl)amino]-8-fluoro-

95%

Reagent Code: #228508
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CAS Number 915369-88-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 330.7 g/mol
Formula C₁₆H₉ClF₂N₄
inventory_2 Storage & Handling
Storage 2-8°C, dry, closed

description Product Description

Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly EGFR inhibitors like Afatinib, in targeted cancer therapies. Its structure enables binding to specific enzyme sites, making it valuable in developing drugs that inhibit abnormal cell growth. Commonly applied in pharmaceutical research for treating solid tumors, such as non-small cell lung cancer. Also utilized in the preparation of small molecule inhibitors that block signaling pathways in cancer cells. Shows high potency in compounds designed to overcome drug resistance in tumor cells.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿70,640.00

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