4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]
98%
Reagent
Code: #228459
CAS Number
402855-07-6
science Other reagents with same CAS 402855-07-6
blur_circular Chemical Specifications
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Molecular Information
Weight
404.77 g/mol
Formula
C₁₈H₁₄ClFN₄O₄
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in the development of targeted cancer therapies. It exhibits potential in inhibiting specific signaling pathways involved in tumor growth and progression. Due to its structural features, it enhances selectivity and binding affinity toward epidermal growth factor receptor (EGFR) mutants. Commonly employed in the preparation of active pharmaceutical ingredients (APIs) for non-small cell lung cancer (NSCLC) treatments. Also utilized in structure-activity relationship (SAR) studies to optimize potency and pharmacokinetic properties of oncology drug candidates.
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