PF-06685360
99%
Reagent
Code: #227103
CAS Number
1527475-61-1
blur_circular Chemical Specifications
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Molecular Information
Weight
308.34 g/mol
Formula
C₁₆H₁₆N₆O
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Storage & Handling
Storage
2-8°C
description Product Description
Used in the treatment of advanced solid tumors, particularly in patients with MET exon 14 skipping mutations. It acts as a selective inhibitor of the MET receptor tyrosine kinase, helping to block tumor growth and spread. Currently under clinical investigation for its efficacy in non-small cell lung cancer and other MET-driven cancers. Shows promise due to high potency and ability to cross the blood-brain barrier, potentially addressing central nervous system metastases.
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