PD-166866

10mM in DMSO

Reagent Code: #224196
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CAS Number 192705-79-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 396.44 g/mol
Formula C₂₀H₂₄N₆O₃
badge Registry Numbers
MDL Number MFCD12922514
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in research settings as a potent and selective inhibitor of fibroblast growth factor receptor 1 (FGFR1), this compound plays a key role in studying signaling pathways involved in cell proliferation, differentiation, and survival. It is widely applied in cancer research to investigate the inhibition of FGFR-driven tumor growth, particularly in cancers where FGFR signaling is dysregulated, such as certain types of breast cancer, multiple myeloma, and leukemia. Its ability to cross the blood-brain barrier also makes it valuable in studies targeting central nervous system tumors or neurological disorders involving aberrant FGFR activity. Additionally, it serves as a pharmacological tool to dissect the role of FGFR in developmental biology and tissue repair mechanisms.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,480.00

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