PF-5274857

10mM in DMSO

Reagent Code: #224085
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CAS Number 1373615-35-0

science Other reagents with same CAS 1373615-35-0

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Weight 436.96 g/mol
Formula C₂₀H₂₅ClN₄O₃S
badge Registry Numbers
MDL Number MFCD22420827
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in research settings as a potent and selective inhibitor of c-Met kinase, an enzyme involved in cell signaling pathways associated with tumor growth and metastasis. It demonstrates strong anti-proliferative effects in cancer cell lines that depend on c-Met signaling, making it a valuable tool compound for studying oncogenic processes and evaluating therapeutic strategies targeting receptor tyrosine kinases. Its high selectivity and blood-brain barrier permeability also support its use in models of central nervous system cancers, aiding in the development of brain-penetrant kinase inhibitors.

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inventory 1ml
10-20 days ฿32,300.00

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PF-5274857
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Used primarily in research settings as a potent and selective inhibitor of c-Met kinase, an enzyme involved in cell signaling pathways associated with tumor growth and metastasis. It demonstrates strong anti-proliferative effects in cancer cell lines that depend on c-Met signaling, making it a valuable tool compound for studying oncogenic processes and evaluating therapeutic strategies targeting receptor tyrosine kinases. Its high selectivity and blood-brain barrier permeability also support its use in models of central nervous system cancers, aiding in the development of brain-penetrant kinase inhibitors.
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