PWT143 (ME-401)

10mM in DMSO

Reagent Code: #224080
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CAS Number 1595129-71-7

science Other reagents with same CAS 1595129-71-7

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Weight 678.81 g/mol
Formula C₃₈H₅₀N₂O₉
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in clinical research for the treatment of various B-cell malignancies, including relapsed or refractory non-Hodgkin lymphoma and chronic lymphocytic leukemia. It functions as a selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), a key signaling molecule involved in B-cell proliferation, survival, and migration. By targeting this pathway, it helps suppress abnormal B-cell growth and promotes apoptosis in malignant cells. Currently under investigation in phase 1 and 2 trials to evaluate safety, efficacy, and optimal dosing in hematologic cancers.

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inventory 1ml
10-20 days ฿6,480.00

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PWT143 (ME-401)
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Used in clinical research for the treatment of various B-cell malignancies, including relapsed or refractory non-Hodgkin lymphoma and chronic lymphocytic leukemia. It functions as a selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), a key signaling molecule involved in B-cell proliferation, survival, and migration. By targeting this pathway, it helps suppress abnormal B-cell growth and promotes apoptosis in malignant cells. Currently under investigation in phase 1 and 2 trials to evaluate safety, efficacy, and optimal dosing in hematologic cancers.
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