PI-103 is primarily used in biomedical research as a potent inhibitor of key signaling pathways involved in cell growth and survival. It effectively targets phosphoinositide 3-kinases (PI3K) and mammalian target of rapamycin (mTOR), making it a valuable tool for studying cancer cell proliferation and apoptosis. Due to its ability to cross the blood-brain barrier, PI-103 is also employed in neuroscience research, particularly in studies related to brain tumors and neurodegenerative diseases. Its application helps in understanding the role of the PI3K/Akt/mTOR pathway in tumor development and in evaluating potential therapeutic strategies for cancers resistant to conventional treatments.