PRT062607 (P505-15, BIIB057) HCl
10mM in DMSO
Reagent
Code: #224021
CAS Number
1370261-97-4
blur_circular Chemical Specifications
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Molecular Information
Weight
429.91 g/mol
Formula
C₁₉H₂₃N₉O·HCl
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Storage & Handling
Storage
-20°C
description Product Description
Used in clinical research for the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. It functions as a selective inhibitor of spleen tyrosine kinase (Syk), which plays a key role in immune cell signaling. By blocking Syk, the compound helps reduce inflammation and immune system overactivity. It has been investigated for its potential to decrease joint damage and improve symptoms in inflammatory conditions. Studies also explore its efficacy in respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD) due to its impact on immune cell activation in the lungs.
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