PKM2 inhibitor(compound 3k)
10mM in DMSO
Reagent
Code: #223891
CAS Number
94164-88-2
blur_circular Chemical Specifications
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Molecular Information
Weight
345.48 g/mol
Formula
C₁₈H₁₉NO₂S₂
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Registry Numbers
MDL Number
MFCD31619244
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Storage & Handling
Storage
-20°C
description Product Description
Used in cancer research to target tumor metabolism by selectively inhibiting the PKM2 enzyme, which plays a key role in the Warburg effect—where cancer cells favor glycolysis for energy production even in the presence of oxygen. By modulating PKM2 activity, compound 3k can shift cancer cell metabolism toward a more normal state, reducing proliferation and inducing apoptosis. It shows potential in preclinical studies for suppressing tumor growth in cancers such as lung, breast, and liver carcinomas. Also used as a tool compound to study metabolic reprogramming in cancer cells and to develop combination therapies with other anticancer agents.
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