Used in pharmaceutical research as a potent and selective inhibitor of KIT and PDGFRα kinases, particularly those with activating mutations, involved in cancer cell signaling pathways. Shows promise in targeting tumor growth and proliferation, especially in gastrointestinal stromal tumors (GIST) and hematologic malignancies such as advanced systemic mastocytosis. Its structure enables high binding affinity to specific mutant kinase targets, improving selectivity and reducing off-target effects. Investigated for use in targeted cancer therapies due to its ability to penetrate cellular membranes, including the blood-brain barrier for potential CNS applications, and maintain stability in biological environments. Also employed as a chemical probe to study kinase-dependent cellular processes.