Used in pharmaceutical research as a potent and selective inhibitor of phosphoinositide 3-kinase gamma (PI3Kγ), a key enzyme in inflammatory, immune, and oncogenic signaling pathways. It plays a crucial role in modulating immune responses in the tumor microenvironment, enhancing the efficacy of immunotherapy against cancers such as breast and lung cancer in preclinical models.

Shows promise in the development of targeted therapies for cancer by inhibiting protein kinases that regulate cell proliferation and survival. Also investigated for treating chronic inflammatory and neurodegenerative diseases, including rheumatoid arthritis and multiple sclerosis, due to its blood-brain barrier permeability, neuroprotective properties, good oral absorption, plasma stability, and ability to cross biological barriers in animal studies.

Its structural features enhance binding specificity to PI3Kγ, reducing off-target effects in cellular assays, making it a candidate for oral therapeutics.