N-[5-(isopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide
≥99%
Reagent
Code: #220317
CAS Number
1124381-69-6
blur_circular Chemical Specifications
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Molecular Information
Weight
364.33 g/mol
Formula
C₁₆H₁₅F₃N₆O
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Storage & Handling
Storage
-20°C
description Product Description
Used as a potent and selective inhibitor in biochemical research, particularly targeting kinases involved in inflammatory and oncogenic signaling pathways. It serves as a key intermediate in the development of pharmaceuticals for cancer therapy, especially in studies related to protein kinase B (Akt) inhibition. Its structure enables high binding affinity and selectivity, making it valuable in structure-activity relationship (SAR) studies. Commonly employed in in vitro assays to modulate cellular proliferation, survival, and apoptosis. Also utilized in tracer studies and radiolabeled forms for target engagement assessment in preclinical models.
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