N4-(4-Fluorophenyl)-7-Methoxyquinazoline-4,6-Diamine
98%
science Other reagents with same CAS 1562180-31-7
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Used in research as a kinase inhibitor, particularly targeting tyrosine kinases such as EGFR (Epidermal Growth Factor Receptor) in studies related to cancer therapy. It shows potential in inhibiting specific signaling pathways involved in tumor growth and cell proliferation, especially for lung, breast, and colorectal cancers. Due to its quinazoline structure, it can bind effectively to ATP-binding sites of certain kinases, making it a valuable scaffold in the development of targeted anticancer agents. Also employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates. Additional research explores its anti-inflammatory effects and other biological activities related to intracellular signaling.
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