Used in research as a potent and selective inhibitor of anaplastic lymphoma kinase (ALK), particularly in the development of targeted cancer therapies. It shows high efficacy against ALK-positive non-small cell lung cancer (NSCLC) and is effective in cases resistant to earlier ALK inhibitors. Its structure allows penetration of the blood-brain barrier, making it valuable in treating brain metastases associated with ALK-driven cancers. Commonly employed in preclinical studies to evaluate signaling pathway inhibition and tumor growth suppression.