Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the study of JAK-STAT signaling pathways. Shows promise in the development of treatments for inflammatory diseases, autoimmune disorders, and certain hematological cancers such as myeloproliferative neoplasms. Its structure enables high binding affinity to the ATP-binding site of JAK2, making it a valuable scaffold in designing targeted therapies. Also employed in structure-activity relationship (SAR) studies to optimize kinase inhibitor potency and selectivity.