N-(6-(6-Chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide
95%
Reagent
Code: #218351
CAS Number
1112980-86-5
science Other reagents with same CAS 1112980-86-5
blur_circular Chemical Specifications
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Molecular Information
Weight
476.93 g/mol
Formula
C₂₀H₁₄ClFN₄O₃S₂
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Registry Numbers
MDL Number
MFCD19443166
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Storage & Handling
Density
1.573±0.06 g/cm3
Storage
Room temperature, dry
description Product Description
Used as a potent inhibitor in biochemical research targeting specific kinase enzymes involved in inflammatory pathways and cancer progression. Its structure allows selective binding to ATP-binding sites in kinases, making it valuable in studying signal transduction mechanisms. Commonly applied in assays to evaluate anti-proliferative effects on tumor cells, particularly in models of leukemia and solid tumors. Also utilized in structure-activity relationship (SAR) studies to develop more effective kinase inhibitors. Due to its fluorinated and chlorinated aromatic systems, it exhibits enhanced metabolic stability and membrane permeability, which are advantageous for cellular and in vivo experiments.
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