N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitroquinazolin-4-yl)acetamide
97%
Reagent
Code: #218069
CAS Number
869199-61-1
blur_circular Chemical Specifications
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Molecular Information
Weight
390.75 g/mol
Formula
C₁₇H₁₂ClFN₄O₄
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Registry Numbers
MDL Number
MFCD30536257
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Physical Properties
Boiling Point
674.0±55.0°C at 760 mmHg
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Storage & Handling
Storage
Room temperature, dry seal
description Product Description
Used as an intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure supports binding to tyrosine kinase domains, making it valuable in developing anticancer agents. Commonly applied in pharmaceutical research for designing drugs that inhibit tumor growth, especially in non-small cell lung cancer. Also utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity of kinase inhibitors.
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