N-(4-((6-Methoxy-7-(3-Morpholinopropoxy)quinazolin-4-yl)aMino)phenyl)benzaMide

10mM in DMSO

Reagent Code: #216345
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CAS Number 331771-20-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 513.6 g/mol
Formula C₂₉H₃₁N₅O₄
badge Registry Numbers
MDL Number MFCD08703125
thermostat Physical Properties
Melting Point 117-120 °C
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used as a potent inhibitor in targeted cancer therapies, particularly in the treatment of certain tyrosine kinase-driven tumors. It interferes with signaling pathways involved in cell proliferation and survival, especially those associated with epidermal growth factor receptor (EGFR) and related kinases. Its structure allows selective binding to mutant forms of these receptors, making it effective in cancers like non-small cell lung carcinoma. The compound is studied for its ability to overcome resistance seen with earlier generation inhibitors, providing a therapeutic option in resistant or relapsed cases. It is also explored in combination therapies to enhance antitumor efficacy and improve patient outcomes.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,600.00

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