Used primarily as a selective inhibitor of RIPK1 (receptor-interacting protein kinase 1), it plays a key role in blocking necroptosis, a form of regulated cell death. This makes it valuable in research focused on ischemic injuries, such as stroke and myocardial infarction, where cell death contributes to tissue damage. It has shown protective effects in models of brain, kidney, and liver injury by reducing inflammation and cell death. Also used in studies of neurodegenerative diseases, including Alzheimer's and Parkinson's, to explore pathways that preserve neuronal viability. Its application extends to inflammatory conditions and sepsis research due to its ability to modulate immune responses and improve survival in animal models. Widely utilized in preclinical studies to understand cell death mechanisms and evaluate potential therapeutic strategies.