NMS-P118
10mM in DMSO
Reagent
Code: #216236
CAS Number
1262417-51-5
blur_circular Chemical Specifications
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Molecular Information
Weight
395.42 g/mol
Formula
C₂₀H₂₄F₃N₃O₂
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in cancer research, particularly for the treatment of hematological malignancies such as leukemia and lymphoma. It functions as a potent and selective inhibitor of protein kinase C (PKC) isoforms, which play key roles in cell proliferation and survival signaling pathways. By targeting specific PKC variants, it helps disrupt abnormal signaling in cancer cells, leading to reduced tumor growth and induction of apoptosis. Its selectivity makes it a valuable tool for studying PKC-dependent mechanisms and a candidate for targeted therapy development with potentially fewer off-target effects. Currently, it is utilized in preclinical studies to evaluate efficacy, pharmacokinetics, and combination strategies with other anticancer agents.
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