4-Amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide

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Reagent Code: #215933
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CAS Number 942437-37-8

science Other reagents with same CAS 942437-37-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 354.38 g/mol
Formula C₁₉H₁₉FN₄O₂
badge Registry Numbers
MDL Number MFCD21337369
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of anaplastic lymphoma kinase (ALK). It shows promising activity against ALK-driven cancers, particularly non-small cell lung cancer (NSCLC) with ALK gene rearrangements. The compound effectively crosses the blood-brain barrier, making it valuable in treating brain metastases associated with ALK-positive tumors. Its high selectivity reduces off-target effects, improving therapeutic efficacy and patient tolerance in clinical settings.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿2,570.00
inventory 10mg
10-20 days ฿4,180.00
inventory 25mg
10-20 days ฿8,010.00

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4-Amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
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Used in pharmaceutical research as a potent and selective inhibitor of anaplastic lymphoma kinase (ALK). It shows promising activity against ALK-driven cancers, particularly non-small cell lung cancer (NSCLC) with ALK gene rearrangements. The compound effectively crosses the blood-brain barrier, making it valuable in treating brain metastases associated with ALK-positive tumors. Its high selectivity reduces off-target effects, improving therapeutic efficacy and patient tolerance in clinical settings.

Used in pharmaceutical research as a potent and selective inhibitor of anaplastic lymphoma kinase (ALK). It shows promising activity against ALK-driven cancers, particularly non-small cell lung cancer (NSCLC) with ALK gene rearrangements. The compound effectively crosses the blood-brain barrier, making it valuable in treating brain metastases associated with ALK-positive tumors. Its high selectivity reduces off-target effects, improving therapeutic efficacy and patient tolerance in clinical settings.

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