Used in pharmaceutical research as a potent and selective inhibitor of tyrosine kinases, particularly targeting EGFR (epidermal growth factor receptor) mutants, including T790M and C797S variants associated with resistance in non-small cell lung cancer. Demonstrates strong antiproliferative activity in cancer cell lines and is investigated for overcoming drug resistance in targeted cancer therapies. Its structure enables improved binding affinity and selectivity, making it a valuable scaffold in the development of next-generation kinase inhibitors. Also employed in studies exploring combination therapies to suppress tumor growth and delay resistance onset.