N-Benzyl-4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide
97%
Reagent
Code: #215486
CAS Number
403718-45-6
science Other reagents with same CAS 403718-45-6
blur_circular Chemical Specifications
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Molecular Information
Weight
455.45 g/mol
Formula
C₂₃H₁₆F₃N₃O₂S
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Storage & Handling
Density
1.48±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used in pharmaceutical research as a potent inhibitor of Janus kinase 2 (JAK2), particularly in the development of targeted therapies for inflammatory diseases and certain cancers. Shows promising activity in suppressing cytokine signaling pathways involved in autoimmune disorders such as rheumatoid arthritis and psoriasis. Also investigated for its potential in treating myeloproliferative neoplasms driven by JAK2 mutations. High selectivity enhances its utility in minimizing off-target effects during therapeutic development.
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