Methyl (4,6-diaMino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyriMidin-5-yl)(Methyl)carbaMate

10mM in DMSO

Reagent Code: #204463
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CAS Number 625115-55-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 422.4 g/mol
Formula C₂₀H₁₉FN₈O₂
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in pharmaceutical research as a potent inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcription regulation. This compound shows promise in oncology for disrupting cancer cell proliferation and inducing apoptosis, especially in hematological malignancies. It is studied for its ability to suppress short-lived oncoproteins by blocking RNA polymerase II phosphorylation. Its selectivity and potency make it a candidate for targeted cancer therapy development. Also used as a biochemical tool to study CDK-mediated signaling pathways in cellular models.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿3,780.00

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