Motesanib
10mM in DMSO
Reagent
Code: #204361
CAS Number
453562-69-1
science Other reagents with same CAS 453562-69-1
blur_circular Chemical Specifications
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Molecular Information
Weight
373.46 g/mol
Formula
C₂₂H₂₃N₅O
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Registry Numbers
MDL Number
MFCD10567689
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of advanced solid tumors, particularly in clinical studies for non-small cell lung cancer and thyroid cancer. It functions as a selective inhibitor of vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptor (PDGFR), and Kit, which are involved in tumor angiogenesis and growth. By blocking these receptors, it helps suppress the formation of new blood vessels that support tumor progression. Investigated in combination with other anticancer agents to enhance therapeutic efficacy.
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