Used in research settings as a selective inhibitor of glycogen synthase kinase-3 (GSK-3), aiding studies related to neurodegenerative diseases, mood disorders, and cancer. It helps modulate cellular signaling pathways, particularly the Wnt/β-catenin pathway, making it valuable in stem cell research and regenerative medicine. Its trifluoroacetate salt form improves solubility and stability in biological assays. Commonly applied in in vitro models to investigate mechanisms of insulin signaling and neuronal survival.