LDK378.2HCl

10mM in DMSO

Reagent Code: #201817
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CAS Number 1380575-43-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 631.0599999999999 g/mol
Formula C₂₈H₃₇Cl₂N₅O₃S
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in the treatment of ALK-positive non-small cell lung cancer, this compound acts as a potent inhibitor of the anaplastic lymphoma kinase (ALK) enzyme. It is particularly effective against tumors that have developed resistance to earlier generation ALK inhibitors. Its application extends to patients with metastatic disease where targeted therapy is required to suppress tumor growth and improve progression-free survival. Due to its ability to cross the blood-brain barrier, it shows significant activity in controlling central nervous system metastases, which are common in advanced stages of lung cancer. The compound is administered orally and designed for chronic use under medical supervision.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,480.00

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