KN-93 Phosphate
10mM in DMSO
Reagent
Code: #201412
CAS Number
1188890-41-6
blur_circular Chemical Specifications
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Molecular Information
Weight
599.03 g/mol
Formula
C₂₆H₂₉ClN₂O₄S·H₃O₄P
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Registry Numbers
MDL Number
MFCD03788201
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Storage & Handling
Storage
-20°C, avoiding light
description Product Description
Used primarily in biomedical research, this compound serves as a selective inhibitor of calcium/calmodulin-dependent protein kinase II (CaMKII). It is widely applied in studies related to cellular signaling pathways, particularly in the investigation of cardiac function, neuronal activity, and synaptic plasticity. Researchers use it to probe the role of CaMKII in processes such as arrhythmias, heart failure, and memory formation. Due to its ability to block CaMKII activation, it helps in understanding disease mechanisms involving abnormal kinase activity. It is also employed in in vitro models to assess ion channel regulation and electrophysiological behavior in excitable cells.
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