JNK-IN-7 is a potent and selective inhibitor of c-Jun N-terminal kinase (JNK), a key enzyme involved in stress-activated signaling pathways. It is widely used in research to study the role of JNK in cellular processes such as apoptosis, inflammation, and neurodegeneration. Due to its ability to cross the blood-brain barrier, JNK-IN-7 is particularly valuable in neuroscience research, where it helps investigate neuroprotective strategies in models of brain injury, stroke, and neurodegenerative diseases like Alzheimer's and Parkinson’s. It has also been applied in studies exploring insulin resistance and metabolic disorders, as JNK signaling is implicated in the development of type 2 diabetes. In cancer research, JNK-IN-7 is used to probe the dual role of JNK in tumor cell survival and death, supporting the development of targeted therapies. Its selectivity and pharmacokinetic properties make it a useful tool compound in preclinical studies aimed at validating JNK as a therapeutic target.