Used primarily in advanced pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors. It shows particular utility in the development of targeted cancer therapies, where its structure enables selective interaction with ATP-binding sites in protein kinases. Its rigid polycyclic framework enhances binding affinity and metabolic stability, making it valuable in optimizing drug candidates for improved efficacy and pharmacokinetics. Also explored in the design of CNS-active agents due to its ability to cross the blood-brain barrier.