Used in biochemical and cellular research to selectively inhibit IRAK-1 and IRAK-4 kinases, which are key components in the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways. This inhibition helps modulate inflammatory responses, making it a valuable tool for studying autoimmune diseases, chronic inflammation, and innate immune signaling. Frequently applied in assays to assess cytokine production, cell signaling cascades, and pathway validation in immune cells. Also utilized in early-stage research to explore therapeutic strategies for cancers and inflammatory disorders where IRAK activity is dysregulated.