8-methyl-2-(trifluoroacetyl)-1,3,4,5-tetrahydrobenzo[b]-1,6-naphthyridin-10(2H)-one
≥90%
Reagent
Code: #197802
CAS Number
1325306-20-4
blur_circular Chemical Specifications
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Molecular Information
Weight
310.28 g/mol
Formula
C₁₅H₁₃F₃N₂O₂
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Registry Numbers
MDL Number
MFCD19705673
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Its structure supports high binding affinity to enzyme active sites, making it valuable in developing anticancer agents. Also explored in the design of anti-inflammatory and neurodegenerative disease therapeutics due to its ability to cross the blood-brain barrier. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved metabolic stability and selectivity. Additionally, it serves as an internal laboratory standard for quality control and the development of analytical methods in pharmaceutical production processes.
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