2-(7H-pyrrole[2,3-d]pyrimidin-4-yl)-N-isoindole-1,3-dione
95%
Reagent
Code: #196176
CAS Number
741686-49-7
blur_circular Chemical Specifications
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Molecular Information
Weight
264.25 g/mol
Formula
C₁₄H₈N₄O₂
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Registry Numbers
MDL Number
MFCD11045038
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Physical Properties
Boiling Point
538.706 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure enables selective binding to ATP sites in protein kinases, making it valuable in targeted therapies for cancers such as chronic myeloid leukemia and non-small cell lung carcinoma. It is also employed in research for designing inhibitors of tyrosine kinases involved in signal transduction pathways. Due to its planar, heterocyclic framework, it supports the development of small molecule drugs with improved binding affinity and metabolic stability.
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